HDL ('good' cholesterol) is the most consistently suppressed cardiovascular marker on AAS. Even low-dose TRT reduces HDL, and oral or high-dose anabolic cycles can drop HDL below 30 mg/dL — a range associated with significantly elevated coronary artery disease risk.
Oral 17-AA androgens (stanozolol, oxandrolone) cause the most severe HDL suppression, sometimes dropping levels to 15–25 mg/dL during a cycle, which substantially increases atherosclerotic risk.
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Analyze My Bloodwork →GearCheck provides blood marker analysis and harm reduction education. Information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional.